Table 3 Histological scoring across PAM50 subtypes
From: PAM50 Breast Cancer Subtyping by RT-qPCR and Concordance with Standard Clinical Molecular Markers
Grade | ER | PR | HER2 | |
|---|---|---|---|---|
LumA | G1-68 (25%) | Neg-19 (7%) | Neg-16 (6%) | Neg-273 (99%) |
n = 277 | G2-142 (51%) | Pos-258 (93%) | Pos-261 (94%) | Pos-4 (1%) |
G3-39 (14%) | ||||
GX-28 (10%) | ||||
LumB | G1-25 (10%) | Neg-22 (8%) | Neg-68 (26%) | Neg-224 (86%) |
n = 261 | G2-111 (43%) | Pos-239 (92%) | Pos-193 (74%) | Pos-37 (14%) |
G3-111 (43%) | ||||
GX-14 (5%) | ||||
HER2-E | G1-6 (3%) | Neg-63 (36%) | Neg-93 (53%) | Neg-105 (60%) |
n = 174 | G2-65 (37%) | Pos-111 (64%) | Pos-81 (47%) | Pos-69 (40%) |
G3-96 (55%) | ||||
GX-7 (4%) | ||||
Basal | G1-0 (0%) | Neg-63 (90%) | Neg-62 (89%) | Neg-67 (96%) |
n = 70 | G2-4 (6%) | Pos-7 (10%) | Pos-8 (11%) | Pos-3 (4%) |
G3-61 (87%) | ||||
GX-5 (7%) |