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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Biomarker discovery in attention deficit hyperactivity disorder: RNA sequencing of whole blood in discordant twin and case-controlled cohorts

Fig. 3

Pathway analysis of differentially expressed genes common to twins and case–control studies: AKT Pathway. Differentially expressed transcripts identified by both the case–control and twin studies were compared to a pre-curated database of biological pathways to determine whether any pathways were disproportionately affected. The top ranking hit, the AKT pathway, is shown schematically with gene products as polygons connected by lines indicating their known relationships. Transcripts identified in the present analysis are shown in color, with other transcripts in the pathway shown in gray

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