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Table 1 Positional information of the 11 scleroderma-risk single nucleotide polymorphisms and the associated haplotypes

From: Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes

SNP

Haplotype

SNP location

Locus name

rs2205960

chr1:173222336–173287411

Intergenic

TNFSF4

rs10488631

chr7:128945562–129071820

Intergenic

IRF5

rs11642873

chr16: 85956661–85958099

Intergenic

IRF8

rs2056626

chr1:167448647–167467063

Intronic

CD247

rs3790567

chr1:67340123–67361333

Intronic

IL12RB2

rs3821236

chr2:191035723–191071078

Intronic

STAT4

rs77583790

chr3:159907604–159976265

Intronic

SCHIP1-IL12A

rs9373839

chr6:106181815–106339294

Intronic

ATG5

rs5029939

chr6:137849452–137921300

Intronic

TNFAIP3

rs1378942

chr15:74751897–74821981

Intronic

CSK

rs2305743

chr19:18068862–18092777

Intronic

IL12RB1

  1. SNPs from Korman et al. [8] were mapped to haplotype blocks using SNiPA. SNP location was determined using the UCSC Genome Browser
  2. chr chromosome, rs reference SNP, SNP single nucleotide polymorphism