Figure 1From: MicroRNA-34a modulates genes involved in cellular motility and oxidative phosphorylation in neural precursors derived from human umbilical cord mesenchymal stem cells MiRNome analysis of umbilical cord MSCs and differentiated neural precursors. (A) (upper and middle) Histograms showing the induction of neural differentiation in WJ-MSCs. WJ-MSCs were subjected into neurogenesis, and total RNAs were collected at the indicated time points for real-time PCR validation. neurofilament (NF), neurogenesis-related genes; nestin, stemness gene. (lower) Immunofluorescence assays on NeuN protein. Day 3 neuronal precursors derived from WJ-MSC were used. (B) A heat map shows the miRNA expression patterns in WJ-MSCs (0d) and derived neural precursors which were differentiated for 9 days (9d). MiRNAs in red, increased expression; in blue, decreased.Back to article page