Figure 5

Differential gene expression induced by a high-fat diet in the 4 segments of the intestine. (A) The number of genes showing at least 2-fold up or down-regulation in the proximal, middle or distal part of the small intestine or in the colon in 4 and 21-month-old mice. (B) IPA analysis revealed the major functional categories to which the differentially expressed genes in the small intestine belong.