Figure 1

Analyses of stability and reliability of MRF methods (by using single HPRD PPI network for endocrine disease class). (a) The variation of posterior probabilities for adjacent steps of the IMRF₁ method. (b) The posterior probability distribution of IMRF₁ method. There are only 5.7% of unknown vertices are predicted with probability larger than 0.065, which means only a small amount significant vertices are predicted with higher probabilities. (c) The variation of posterior probabilities for adjacent steps of the MRF-Deng method; (d) The posterior probability distribution of MRF-Deng method. There are almost 23.3% of unknown vertices are predicted with probability larger than 0.97, which means too many vertices are predicted with very high probabilities.