Platform-independent gene expression signature differentiates sessile serrated adenomas/polyps and hyperplastic polyps of the colon

Table 1 Up-regulated pathways (GO categories)

Category	Pathway	FDR^a
Cell adhesion
	CALCIUM INDEPENDENT CELL CELL ADHESION	0.022
	CELL SUBSTRATE ADHERENS JUNCTION	0.042
Cell growth and death
	CELL STRUCTURE DISASSEMBLY DURING APOPTOSIS	0.033
	POSITIVE REGULATION OF CELL PROLIFERATION	0.033
Immune system
	INFLAMMATORY RESPONSE	0.033
	IMMUNOLOGICAL SYNAPSE	0.045
Signal transduction
	POSITIVE REGULATION OF SECRETION	0.045
	G PROTEIN COUPLED RECEPTOR PROTEIN SIGNALING	0.042
	SECOND MESSENGER MEDIATED SIGNALING	0.045
Metabolism
	AROMATIC COMPOUND METABOLIC PROCESS	0.022
	HETEROCYCLE METABOLIC PROCESS	0.022
Differentiation
	CELLULAR MORPHOGENESIS DURING DIFFERENTIATION	0.045
Cellular component organization
	EXTRACELLULAR STRUCTURE ORGANIZATION AND BIOGENESIS	0.042
Neuron development
	AXONOGENESIS	0.042
	NEURITE DEVELOPMENT	0.045

ISSN: 1755-8794