Fig. 3

a Log-transformed P-values of association tests determined by logistic regression analysis with odds ratio increments of 0.1. The sample size was 1000 for both cases and controls. The penetrance for the genotype with the lowest risk was 0.03, and the odds ratio (r) ranged from 1.1 to 2.0 in increments of 0.1. b Log-transformed P-values of association tests determined by logistic regression analysis with odds ratio increments of 0.2. The sample size was 1000 for both cases and controls. The penetrance for the genotype with the lowest risk was 0.03, and the odds ratio (r) ranged from 1.2 to 2.0 in increments of 0.2. Red and blue circles/lines indicate values for risk allele frequencies shown in red and blue, respectively