Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Table 1 NSCLC cell lines used in this work

Cell line	Type of cancer	P53 status
A427	NSCLC adenocarcinoma	wt
A549	NSCLC adenocarcinoma	wt
COR-L23	NSCLC large cell adenocarcinoma	P53 inactivating alteration
DV-90	NSCLC adenocarcinoma	wt
NCI-H1395	NSCLC adenocarcinoma	wt
NCI-H1944	NSCLC adenocarcinoma	wt
NCI-H2228	NSCLC adenocarcinoma	P53 inactivating alteration
NCI-H292	Mucoepidermal lung carcinoma	wt

ISSN: 1755-8794