Table 3 Association of previously reported GDM loci with risk of GDM according to both criteria
SNP | EA | Chr | Gene/nearest gene | Location | WHO 1999 | WHO 2013 | n | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | CI(lower) | CI(upper) | p-value | OR | CI(lower) | CI(upper) | p-value | ||||||
rs9939609 | A | 16 | FTO | intron | 1.04 | 0.86 | 1.26 | 0.67 | 0.98 | 0.88 | 1.10 | 0.83 | 3120 |
rs2796441 | G | 9 | TLE 1 | intergenic | 0.99 | 0.84 | 1.16 | 0.92 | 1.07 | 0.97 | 1.17 | 0.15 | 3905 |
rs560887 | C | 2 | G6PC2/ABCB11 | intron | 1.18 | 0.92 | 1.52 | 0.19 | 1.11 | 0.96 | 1.28 | 0.13 | 3910 |
rs11708067 | A | 3 | ADCY5 | intron | 0.98 | 0.81 | 1.18 | 0.86 | 0.88 | 0.79 | 0.99 | 0.037 | 3877 |
rs1111875 | C | 10 | HHEX | intergenic | 0.90 | 0.77 | 1.06 | 0.22 | 1.05 | 0.96 | 1.16 | 0.24 | 3901 |
rs10811661 | T | 9 | CDKN2A/2B | intergenic | 0.99 | 0.77 | 1.26 | 0.93 | 1.08 | 0.94 | 1.25 | 0.23 | 3890 |
rs4402960 | T | 3 | IGF2BP2 | intron | 1.02 | 0.87 | 1.20 | 0.77 | 0.95 | 0.86 | 1.04 | 0.29 | 3750 |
rs13266634 | C | 8 | SLC30A8 | coding-missense | 0.96 | 0.79 | 1.17 | 0.75 | 0.97 | 0.87 | 1.08 | 0.61 | 3898 |
rs7903146 | T | 10 | TCF7L2 | Intronic/promoter | 1.13 | 0.95 | 1.35 | 0.14 | 1.01 | 0.916 | 1.12 | 0.76 | 3543 |
rs10830963 | G | 11 | MTNR1B | intron | 0.89 | 0.75 | 1.05 | 0.20 | 0.98 | 0.89 | 1.08 | 0.69 | 3714 |
rs1801282 | C | 3 | PPARG | Coding-missense | 0.86 | 0.89 | 1.12 | 0.22 | 0.99 | 0.93 | 1.08 | 0.21 | 3652 |
rs10010131 | G | 4 | WFS1 | intron | 1.13 | 0.95 | 1.36 | 0.16 | 0.99 | 0.90 | 1.10 | 0.99 | 3843 |
rs5219 | T | 11 | KCNJ11 | coding-missense | 1.21 | 1.03 | 1.42 | 0.019 | 1.00 | 0.90 | 1.10 | 0.99 | 3595 |