Fig. 1

RNA sequencing of whole blood from ADHD Cases versus Matched Controls. Stabilized whole blood was sequenced, aligned, and then counted into UCSC-defined transcripts, expressed as reads per K of transcript per M of total assigned reads per subject (RPKM). Transcripts were filtered for > 0.01 RPKM in 70% of samples in at least 1 of the 2 groups, resulting in 95,511 transcripts remaining. The RPKM level of each transcript (colored squares) is expressed as the mean in Controls (X axis) versus the mean in ADHD cases (Y axis) for each of the transcripts, and plotted on log2 scale. The central green line is a slope of 1, bounded on each side by twofold change lines. Black line is the actual fit of the data distribution, defined by the equation in the upper left