Fig. 3
From: A novel mutation of COL2A1 in a large Chinese family with avascular necrosis of the femoral head
A, B the pre-operation and post-operation radiographs of IV3. C, D the pre-operation and post-operation radiographs of IV7. The pre-operation radiographs of both patients (IV3 and IV7) showed severe collapse and deformity of the femoral heads with hip joint space narrowing and osteoarthritis. E The radiograph of V2 showed the surface of the femoral head is smooth with no joint space narrowing, but there is localized increasing of bone density and sclerosis at weight-bearing region of the left femoral head. F MRI of V2 showed the crescent-shaped hyperintensity region on T2W and lower and uneven signal of necrosis region on T1W in the left femoral head