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Table 9 SNP–SNP interaction models analyzed by the MDR method

From: Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population

Model

Training Bal. Acc

Testing Bal. Acc

CVC

OR (95% CI)

p

rs3821236

0.532

0.515

9/10

1.35(1.03–1.77)

0.032*

rs3821236, rs897200

0.542

0.523

5/10

1.38(1.08–1.77)

0.011*

rs3821236, rs11889341, rs897200

0.555

0.499

5/10

1.52(1.19–1.96)

0.001*

rs3821236, rs11893432, rs11889341, rs897200

0.572

0.496

8/10

1.73(1.35–2.22)

 < 0.0001*

rs3821236, rs11893432, rs11889341, rs7574865, rs897200

0.579

0.501

10/10

1.85(1.43–2.38)

 < 0.0001*

  1. MDR multifactor dimensionality reduction, Bal. Acc. balanced accuracy, CVC cross–validation consistency, OR odds ratio,
  2. CI: confidence interval;
  3. p values were calculated using χ2 tests, *p < 0.05 indicates statistical significance
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BMC Medical Genomics

ISSN: 1755-8794

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