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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Genetic and molecular dynamics analysis of two variants of the COL4A5 gene causing Alport syndrome

Fig. 5

The molecular dynamics simulation lasted for 100 ns to obtain local magnification diagrams of the conformations of wild-α5(IV), mute1-α5(IV), and mute2-α5(IV) chains. (A) Enlarged view of residues after amino acid 1472 of α5(IV) following molecular dynamics simulations. (B) The blue label serves as a means of magnification to verify the presence of amino acids inserted at positions 1432–1433

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