Table 2 Genotype and allele frequencies of ITGB2 rs2070946 SNP (T/C) in RA patients and healthy controls
Genetic model | rs2070946 Genotype/ allele | Frequency, n (%) | Adjusted OR (95%CI) | Pa,b value | |
|---|---|---|---|---|---|
Healthy controls (n = 60) | RA (n = 70) | ||||
Codominant | TT | 19 (31.7) | 5 (7.1) | 1 | |
TC | 35 (58.3) | 30 (42.9) | 3.257 (1.114–8.645) | 0.245 | |
CC | 6 (10) | 35 (50) | 22.17 (5.902–85.84) | 0.0005 | |
Dominant | TT | 19 (31.7) | 5 (7.1) | 1 | |
TC + CC | 41 (68.3) | 65 (92.9) | 6.024 (2.031–15.48) | 0.0025 | |
Recessive | TT + TC | 54 (90) | 35 (50) | 1 | |
CC | 6 (10) | 35 (50) | 9 (3.338–22.75) | 0.0005 | |
Overdominant | TT + CC | 25 (41.7) | 40 (57.1) | 1 | |
TC | 35 (58.3) | 30 (42.9) | 0.5357 (0.261–1.063) | 0.565 | |
Allelic | T | 73 (0.61) | 40 (0.29) | 1 | |
C | 47 (0.39) | 100 (0.71) | 3.883 (2.334–6.445) | 0.0005 | |