Table 3 Genotype and allele frequencies of ITGB2 rs2070946 SNP (T/C) in OA patients and healthy controls
Genetic model | rs2070946 Genotype/ allele | Frequency, n (%) | Adjusted OR (95%CI) | Pa,b-value | |
|---|---|---|---|---|---|
Healthy controls (n = 60) | OA (n = 70) | ||||
Codominant | TT | 19 (31.7) | 3 (4.3) | 1 | |
TC | 35 (58.3) | 33 (47.1) | 5.971 (1.604–20.17) | 0.025 | |
CC | 6 (10) | 34 (48.6) | 35.89 (7.485–130.1) | 0.0005 | |
Dominant | TT | 19 (31.7) | 3 (4.3) | 1 | |
TC + CC | 41 (68.3) | 67 (95.7) | 10.35 (3.004–34.19) | 0.0005 | |
Recessive | TT + TC | 54 (90) | 36 (51.4) | 1 | |
CC | 6 (10) | 34 (48.6) | 8.5 (3.15–21.5) | 0.0005 | |
Overdominant | TT + CC | 25 (41.7) | 37 (52.9) | 1 | |
TC | 35 (58.3) | 33 (47.1) | 0.637 (0.313–1.262) | > 0.999 | |
Allelic | T | 73 (0.61) | 39 (0.28) | 1 | |
C | 47 (0.39) | 101 (0.72) | 4.022 (2.41–6.708) | 0.0005 | |