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Table 2 Description of the traditional feature selection methods and the mean AUROC score in each setting

From: miRDM-rfGA: Genetic algorithm-based identification of a miRNA set for detecting type 2 diabetes

Traditional feature selection methods

Setting 7

Setting 8

Setting 9

Feature selection models

Univariate feature selection (f_classif)

Lasso (Logistic regression using L1 regularization)

Lasso (Logistic regression using L1 regularization)

Selection methods

SelectKBest

(top 3)

SelectFromModel (top 3)

SelectFromModel (top 3)

T2DM classification model

Random forest

Lasso

Random forest

Selected miRNAs

hsa-miR-6820–5p, hsa-miR-29b-2-5p, and hsa-miR-1307-3p

hsa-miR-22-3p, hsa-miR-92a-3p, and hsa-miR-181a-5p

hsa-miR-22-3p, hsa-miR-92a-3p, and hsa-miR-181a-5p

Fold for cross-validation of test data

3

3

3

Mean AUROC score by threefold cross-validation in test set and standard deviation

0.72 ± 0.08

0.64 ± 0.05

0.52 ± 0.02