Fig. 2

Construction of the NKRLSig model based on the target genes A A Venn diagram depicts 115 overlapping mRNAs considered NK cell-related, including 85 down-regulated genes and 30 up-regulated genes. B Heat map plot differentially expressed NKRLSig. C Volcano plot differentially expressed NKRLSig. D Forest plot showing 17 mRNAs with hazard ratios (95%confidence intervals) and P values based on the result of univariate Cox regression analysis. E–F mRNAs screened by the LASSO-Cox regression model