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Table 1 Information on GWASs for exposure and outcome

From: Does inflammatory bowel disease promote kidney diseases: a mendelian randomization study with populations of European ancestry

Traits

Cases

Controls

Year

Number of SNPs

Sample size

Population

PMID/Consortium

IgA nephropathy

977

4,980

2010

278,077

5,957

European

20,595,679

Membranous nephropathy

2,150

5,829

2020

5,327,688

7,979

European

32,231,244

Glomerulonephritis

4,613

214,179

2021

16,380,466

218,792

European

IEU GWAS datasets

Nephrotic syndrome

480

214,619

2021

16,380,437

215,099

European

IEU GWAS datasets

Diabetic nephropathy

3,283

181,704

2021

16,380,336

184,987

European

IEU GWAS datasets

Chronic kidney disease

12,385

104,780

2016

2,191,877

117,165

European

26,831,199/ CKDGen

Urolithiasis

3,625

459,308

2018

9,851,867

462,933

European

MRC-IEU

210 kinds of T-cell traits and markers

-

-

2018

10,534,735

3,757

European

3,292,928

Inflammatory bowel disease

38,155

33,977

2015

157,116

86,640

European

26,192,919/ IIBDGC

Crohn’s disease

20,550

41,642

2015

124,888

62,192

European

26,192,919/ IIBDGC

Ulcerative colitis

17,647

47,179

2015

156,116

64,826

European

26,192,919/ IIBDGC