Table 3 MR results for the correlation between smoking and alcohol drink behaviors
From: Smoking, alcohol consumption and risk of Dupuytren’s disease: a Mendelian randomization study
Exposure | Outcome | SNP, N | Method | OR | 95% CI | P-value |
|---|---|---|---|---|---|---|
Drinks per week | Age of initiation | 37 | IVW | 0.96 | (0.866,1.064) | 4.38E-01 |
MR-Egger | 1.073 | (0.909,1.266) | 4.12E-01 | |||
WME | 1.053 | (0.970,1.142) | 2.18E-01 | |||
Drinks per week | Cigarettes per day | 37 | IVW | 1.063 | (0.886,1.276) | 5.12E-01 |
MR-Egger | 0.889 | (0.661,1.198) | 4.45E-01 | |||
WME | 0.995 | (0.844,1.172) | 9.48E-01 | |||
Drinks per week | Smoking cessation | 36 | IVW | 1.066 | (0.908,1.252) | 4.34E-01 |
MR-Egger | 1.029 | (0.779,1.360) | 8.39E-01 | |||
WME | 1.066 | (0.901,1.263) | 4.55E-01 | |||
Drinks per week | Smoking initiation | 36 | IVW | 1.376 | (1.122,1.688) | 2.21E-03 |
MR-Egger | 0.911 | (0.678,1.224) | 5.41E-01 | |||
WME | 0.96 | (0.851,1.083) | 5.06E-01 | |||
Age of initiation | Drinks per week | 7 | IVW | 0.782 | (0.677,0.902) | 7.71E-04 |
MR-Egger | 1.199 | (0.886,1.623) | 2.92E-01 | |||
WME | 0.723 | (0.637,0.820) | 4.56E-07 | |||
Cigarettes per day | Drinks per week | 22 | IVW | 1.013 | (0.985,1.042) | 3.73E-01 |
MR-Egger | 0.977 | (0.932,1.024) | 3.34E-01 | |||
WME | 0.997 | (0.977,1.018) | 8.12E-01 | |||
Smoking cessation | Drinks per week | 8 | IVW | 0.987 | (0.914,1.066) | 7.44E-01 |
MR-Egger | 0.913 | (0.715,1.165) | 4.91E-01 | |||
WME | 0.951 | (0.905,0.999) | 4.50E-02 | |||
Smoking initiation | Drinks per week | 85 | IVW | 1.138 | (1.099,1.178) | 3.55E-13 |
MR-Egger | 1.234 | (1.036,1.471) | 2.10E-02 | |||
WME | 1.129 | (1.095,1.164) | 1.04E-14 |