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Table 4 Multivariable MR results for smoking or alcohol drink behaviors on DD after adjusting for each other

From: Smoking, alcohol consumption and risk of Dupuytren’s disease: a Mendelian randomization study

Exposure

Conditional F-statistics

OR

95%CI

P-value

(Age of Initiation + Drinks Per Week)

 Age of Initiation

9

0.735

(0.316,1.712)

4.76E-01

 DrinksPerWeek

65.3

3.042

(1.763,5.251)

6.47E-05

(Cigarettes Per Day + Drinks Per Week)

 Cigarettes Per Day

24.8

1.016

(0.827,1.247)

8.79E-01

 Drinks Per Week

48.2

2.871

(1.725,4.778)

3.40E-05

(Smoking Cessation + Drinks Per Week)

 Smoking Cessation

9.2

0.768

(0.497,1.188)

2.36E-01

 Drinks Per Week

38.9

2.919

(1.708,4.990)

8.93E-05

(Smoking Initiation + Drinks Per Week)

 Smoking Initiation

30.5

1.024

(0.803,1.305)

8.49E-01

 Drinks Per Week

21.8

2.434

(1.361,4.355)

2.72E-03

  1. Abbreviations: OR Odds ratio, CI Confidence interval
  2. a The results for multivariable Mendelian randomization analyses were based on multivariable inverse variance weighted method