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Table 2 Distribution of genotype, allele frequencies and genetic models of rs9939609 between PCOS cases and controls

From: Association of FTO gene variant rs9939609 with polycystic ovary syndrome from Gujarat, India

SNP

Genotype/ Allele

Case (%)

Control (%)

p-value

χ2

OR (95% CI)

rs9939609

TT

27 (43.55)

21 (40.38)

0.25

0.68

1.27

0.15

1.71

TA

12 (19.35)

16 (30.77)

0.69 to 4.51

AA

23 (37.10)

15 (28.85)

0.83

0.33 to 2.00

T

33 (53.23)

29 (55.77)

0.78

0.07

0.90

A

29 (46.77)

23 (44.23)

0.43 to 1.83

Dominant model

T/T

35 (56.45)

31 (59.62)

0.73

0.11

1.13

T/A + A/A

0.55 to 2.38

Recessive model

T/A + T/T

39 (62.90)

37 (71.15)

0.35

0.86

1.45

A/A

0.65 to 3.13

Heterozygous model

T/T + A/A

50 (80.65)

36 (69.23)

0.15

1.98

0.54

T/A

0.23 to 1.27

  1. χ2 chi Square, OR odds ratio, CI confidence interval
  2. p < 0.05 significant