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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Meta-analysis of integrated ChIP-seq and transcriptome data revealed genomic regions affected by estrogen receptor alpha in breast cancer

Fig. 1

An overview of the meta-analysis steps performed in the present study. ChIP-seq datasets were retrieved from SRA-NCBI and ENA-EBI databases. Pre-processing and re-analyzing steps of datasets were conducted. Then, batch effects removal and meta-analysis were performed. Subsequently, peak set functional enrichment analysis (PSFEA) and ChIP Enrichment Analysis for meta-DBSs-associated common genes were performed using the Cistrome-GO database and ChEA3 database, respectively. The packages and methods employed are in bold form. TFBSs Transcription factor binding sites, DBSs Differentially bound sites, Meta-DBSs Meta-differentially bound sites

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BMC Medical Genomics

ISSN: 1755-8794

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