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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Meta-analysis of integrated ChIP-seq and transcriptome data revealed genomic regions affected by estrogen receptor alpha in breast cancer

Fig. 3

A workflow for integration and meta-analysis of ChIP-seq TFBSs scores from several studies. Datasets were selected based on the same criteria and re-analyzed with the same platform. Then samples were integrated, normalized, and meta-analyzed. This process was performed for MCF7 cell lines, and meta-DBSs were obtained. Next, meta-DBSs-associated genes were identified with peak annotation. The packages used in each step are marked in blue. TFBSs Transcription factor binding sites, DBSs Differentially bound sites, Meta-DBSs Meta-differentially bound sites

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BMC Medical Genomics

ISSN: 1755-8794

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