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Table 2 Identified DBSs/ meta-DBSs through individual/ meta-analysis on eight studies of the MCF7 and T47D cell lines treated with 10 nM and 100 nM E2

From: Meta-analysis of integrated ChIP-seq and transcriptome data revealed genomic regions affected by estrogen receptor alpha in breast cancer

Analysis

Accession number

Cell line

Treatment

Dose (nM)

DBSs or Meta-DBSs (n)

Associated genes (n)

Individual analysis

GSE94023

MCF7

E2

10

38,963

13,982

GSE99626

15,372

9,013

GSE67295

29,145

11,531

GSE115607

21,939

11,020

GSE80367

T47D

4,877

3,081

GSE23893

T47D

100

1,882

1,320

GSE23893

MCF7

11,155

6,272

GSE54855

10,343

5,710

GSE59530

29,915

10,817

Meta-analysis

GSE94023

MCF7

10

23,308

10,503

GSE99626

GSE67295

GSE115607

GSE23893

100

7,796

4,591

GSE54855

GSE59530

  1. DBSs differentially bound sites, Meta-DBSs meta-differentially bound sites, nM Nanomolar