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Fig. 2 | BMC Medical Genomics

Fig. 2

From: An alpha-helix variant p.Arg156Pro in LMNA as a cause of hereditary dilated cardiomyopathy: genetics and bioinfomatics exploration

Fig. 2

(A)Venn diagram depicted the DEGs by the 3 Mice cohorts. 3 of 52 common DEGs were identified as Key Gene List1. (B) Venn diagram showed the intersection between Mice Model common DEGs, Human LMNA-DCM DEGs and LMNA-specific DEGs. The overlapping DEGs were identified as Key Gene List2 and List3. (C) The enrichment analysis of the 52 Mice Model common DEGs by Metascape. (D) Analysis of function and enrichment of Human LMNA-DCM DEGs. The enriched items of up-regulated genes were red, while the enriched items of down-regulated genes were blue. (E)The enrichment analysis of the 119 LMNA-specific DEGs

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