Table 1 Demographics of the enrolled patients in this metabolomics pilot study

1

Age (years)

58 ± 10

60 ± 15

0.4

2

Gender

15/15

15/15

0.3

3

Temperature (°C)

37.1 ± 0.7

37.9 ± 0.9

0.01

4

WBC counts (×10⁹/L)

7.26 ± 1.32

14.05 ± 7.36

0.02

5

Serum CRP (mg/L)

2.32 ± 1.21

11.54 ± 5.78

0.001

6

Serum PCT (ng/mL)

0.27 (0.2–0.54)

2.28 (0.6–7.12)

0.005

7

BUN (mmol/L)

5.02 ± 3.18

8.01 ± 3.21

0.005

8

Serum Creatinine (mmol/dL)

63.5 (39.5–75.3)

79.5 (55.5–140)

0.001

9

APACHE II score

11 ± 9

22 ± 7

10

SOFA score

9 ± 4

11

Pulmonary

12

Urinary

11 (31.4)

13

Bacteremia

9 (25.7)

14

Gram-positive bacteria

17 (48.6)

15

Gram-negative bacteria

34 (97.1)

16

Fungi

22 (62.90)