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Table 2 Metabolite differences that were identified between the different groups

From: Serum metabolite profiling reveals metabolic characteristics of sepsis patients using LC/MS-based metabolic profiles: a cross-sectional study

ID

MZ

name

RT

VIP

Adust p value

FC(sepsis/control)

HMDB0248231

219.113

1-Methyl-L-tryptophan

8.86

1.61

2.03E-04

1.28

HMDB0000933

229.1373

2Z-Dodecenedioic acid

4.90

1.05

4.18E-03

0.66

HMDB0001494

140.9958

Acetyl phosphate

16.34

2.34

7.62E-06

1.21

LMSP01040003

288.2901

C17 Sphinganine

7.39

1.43

1.77E-03

1.16

LMSP01050004

416.2528

C19 Sphingosine-1-phosphate

4.90

1.30

6.62E-05

0.59

HMDB0006510

494.3245

Cervonyl carnitine

8.58

1.16

2.98E-04

0.55

HMDB0002586

473.2649

Chenodeoxycholic acid 3-sulfate

8.46

1.01

2.90E-02

1.13

HMDB0000562

114.0663

Creatinine

0.74

1.20

7.05E-04

1.75

HMDB0242127

393.2863

Docosanedioic acid

8.37

1.45

2.64E-02

1.09

HMDB0001999

303.2319

Eicosapentaenoic Acid

9.78

1.08

8.14E-04

0.36

HMDB0000174

187.0542

Fucose

0.78

1.23

1.39E-04

0.59

HMDB0000148

148.0582

Glutamate

0.73

1.09

5.87E-04

0.65

HMDB0252892

285.9789

Glyphosine

0.70

1.40

2.11E-05

0.71

LMFA01170040

425.3621

Hexacosanedioic acid

12.75

1.36

3.19E-04

0.59

HMDB0000687

130.0847

Leucine

1.39

1.36

1.26E-03

0.76

HMDB0000159

188.0708

 L-Phenylalanine

4.23

1.69

3.04E-07

0.58

HMDB0010381

480.3082

LysoPC(15:0)

9.30

1.17

2.07E-03

0.67

HMDB0010393

546.3556

LysoPC(20:3(5Z,8Z,11Z))

9.26

1.26

1.12E-04

0.52

HMDB0011475

502.2931

LysoPE(0:0/18:1(11Z))

8.78

1.11

5.18E-04

0.53

HMDB0011482

508.3396

LysoPE(0:0/20:1(11Z))

9.04

1.29

6.62E-05

0.53

HMDB0011483

504.3081

LysoPE(0:0/20:2(11Z,14Z))

8.90

1.17

1.77E-03

0.63

HMDB0011515

526.293

LysoPE(20:3(5Z,8Z,11Z)/0:0)

8.75

1.21

1.84E-04

0.49

LMGP10010933

587.3788

PA(14:0/12:0)

4.76

1.38

2.11E-05

0.55

LMGP01050012

468.3089

PC(14:0/0:0)

8.30

1.28

8.38E-05

0.42

HMDB0010382

496.3407

PC(16:0/0:0)

9.30

1.18

2.39E-04

0.58

HMDB0012108

510.3558

PC(17:0/0:0)

9.92

1.11

5.17E-04

0.53

LMGP01050030

522.3563

PC(18:1(9E)/0:0)

9.58

1.12

5.00E-04

0.55

LMGP01050034

520.3406

PC(18:2(2E,4E)/0:0)

8.89

1.15

3.45E-04

0.48

LMGP01050068

398.2418

PC(9:0/0:0)

8.37

1.38

3.80E-02

1.08

LMGP02010102

490.268

PE(8:0/8:0)

4.73

1.39

2.07E-05

0.56

LMGP04050031

527.3212

PG(19:0/0:0)

4.96

1.30

6.62E-05

0.59

LMGP04010030

441.2013

PG(6:0/6:0)

12.74

1.55

2.01E-05

0.78

LMGP04030093

835.5961

PG(P-20:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

16.30

1.49

5.36E-06

0.33

HMDB0001024

184.9858

Phosphohydroxypyruvic acid

16.34

2.39

3.19E-06

1.23

HMDB0240262

601.3363

PI(18:0/0:0)

4.84

1.29

6.62E-05

0.58

LMGP06050027

649.305

PI(19:0/0:0)

8.90

1.52

1.03E-04

0.63

LMGP06010442

923.6567

PI(19:0/21:0)

10.45

1.11

1.26E-03

2.58

LMGP06010443

937.6551

PI(19:0/22:0)

12.09

1.39

2.11E-05

0.17

LMGP06070002

583.3347

PI(P-18:0/0:0)

9.58

1.34

3.84E-04

0.59

LMGP06030075

913.6358

PI(P-20:0/19:1(9Z))

10.38

1.57

4.46E-06

3.24

LMGP03010027

658.3315

PS(12:0/12:0)

9.25

1.51

8.38E-05

0.59

LMGP03010001

638.3899

PS(12:0/13:0)

5.02

1.31

6.18E-05

0.58

LMGP03050005

478.3294

PS(13:0/0:0)

9.30

1.07

8.78E-04

0.67

LMGP03050030

534.2959

PS(17:0/0:0)

9.30

1.16

3.05E-04

0.67

LMGP03050006

526.3045

PS(18:0/0:0)

9.30

1.22

1.53E-04

0.59

LMGP03050028

538.3135

PS(19:0/0:0)

8.58

1.29

5.69E-04

0.60

LMGP03050020

552.33

PS(20:1(11Z)/0:0)

5.44

1.42

2.07E-05

0.54

LMGP03050026

566.3454

PS(21:0/0:0)

9.58

1.30

5.53E-04

0.61

LMGP03010722

924.6452

PS(22:0/22:1(11Z))

10.63

1.67

1.93E-06

3.66

LMGP03020054

800.5824

PS(O-20:0/18:3(6Z,9Z,12Z))

16.45

1.56

2.30E-06

0.38

HMDB0000277

380.2564

Sphingosine-1-phosphate

8.20

1.91

1.76E-09

0.60

HMDB0000848

428.3736

Stearoylcarnitine

9.30

1.38

2.11E-05

0.55

HMDB0001259

101.0244

Succinic acid semialdehyde

1.35

1.23

6.73E-04

2.29

HMDB0000251

124.0074

Taurine

0.73

1.45

1.60E-04

0.60

HMDB0002581

618.2472

Taurocholic acid 3-sulfate

9.30

1.60

1.93E-06

0.63

HMDB0010562

1045.711

TG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

10.13

1.52

3.41E-06

0.20

HMDB0000929

203.0823

Tryptophan

4.23

1.84

2.30E-06

0.56

HMDB0000158

180.0664

Tyrosine

1.31

1.50

2.25E-04

0.69

HMDB0000883

118.0862

Valine

0.81

1.08

1.25E-03

0.84

  1. MZ, mass-to-charge ratio;VIP, variable importance in projection;FDR_bh, ajust p value; .FC, fold chage of sepsis/control