Table 3 Effect of myopia Traits on other vitreous disordes
From: Mendelian randomization study confirms causal relationship between myopia and vitreous disorders
Expousure | Outcome | SNPs | Methods | OR | 95% CI | P |
|---|---|---|---|---|---|---|
Myopia | Crystalline deposits in vitreous body | 28 | MR Egger | 1.282e + 02 | 3.670e-17–4.479e + 20 | 0.83 |
Weighted median | 1.256e-04 | 4.117e-13–3.831e + 04 | 0.37 | |||
Inverse variance weighted | 2.210e-05 | 1.686e-11–2.898e + 01 | 0.14 | |||
Simple mode | 6.986e-03 | 8.302e-18–5.879e + 12 | 0.78 | |||
Weighted mode | 2.165e-03 | 8.185e-15–5.724e + 08 | 0.65 | |||
Other vitreous opacities | 28 | MR Egger | 3.414e-01 | 7.299e-10–1.597e + 08 | 0.92 | |
Weighted median | 8.349e-03 | 1.389e-06–5.018e + 01 | 0.28 | |||
Inverse variance weighted | 4.127e-01 | 6.552e-04–2.600e + 02 | 0.79 | |||
Simple mode | 3.355e + 02 | 3.964e-05–2.839e + 09 | 0.48 | |||
Weighted mode | 2.693e-03 | 5.600e-09–1.295e + 03 | 0.38 | |||
Vitreous haemorrhage | 28 | MR Egger | 145.078 | 1.664e-03–1.265e + 07 | 0.40 | |
Weighted median | 1.589 | 8.357e-03–3.021e + 02 | 0.86 | |||
Inverse variance weighted | 8.131 | 2.046e-01–3.231e + 02 | 0.26 | |||
Simple mode | 0.719 | 1.164e-05–4.448e + 04 | 0.95 | |||
Weighted mode | 0.719 | 9.172e-05–5.644e + 03 | 0.94 | |||
Other and unspecified disorders of vitreous body | 28 | MR Egger | 18291.566 | 73.495–4552465.865 | < 0.01 | |
Weighted median | 150.033 | 9.709–2318.399 | < 0.01 | |||
Inverse variance weighted | 57.729 | 9.444–352.868 | < 0.01 | |||
Simple mode | 972.333 | 4.167–226879.121 | < 0.01 | |||
Weighted mode | 563.954 | 15.929 –19966.053 | < 0.01 |