Fig. 5

Association between BTNL9 expression and immune infiltrations in THCA. (A) Box plot illustrating the enrichment of 24 subtypes of immune cells in high and low BTNL9 expression groups. (B) Lollipop chart showing the correlation between BTNL9 expression and different immune cells. (C)BTNL9 copy number variations were related to the infiltration levels of B cells, CD8 + T cells, CD4 + T cells, macrophages, neutrophils and dendritic cells in THCA. (D) Correlations between BTNL9 expression and infiltration levels of different immune cells. (E) Heatmap indicating correlations between BTNL9 expression and immune checkpoint genes. THCA, thyroid carcinoma; Tcm cell, central memory T cell; Treg cell, regulatory T cell; Th1 cell, T helper 1 cell; Th2 cell, T helper 2 cell; Tem cell, effector memory T cell; TFH cell, follicular helper T cell; NK cell, natural killer cell; DC, dendritic cells; pDC, plasmacytoid dendritic cells; iDC, interdigitating cell; aDC, activated dendritic cells. *p < 0.05, **p < 0.01, ***p < 0.001