Table 6 Association of CYP4V2 gene SNP polymorphisms with CHD risk stratified analysis by smoking

rs1398007

Co-dominant

CC

107

130

1

111

110

1

CT

120

109

1.31(0.91–1.90)

0.150

102

99

1.03(0.69–1.53)

0.888

TT

29

20

1.86(0.98–3.51)

0.056

18

19

0.89(0.43–1.82)

0.748

Dominant

CC

107

130

1

111

110

1

CT + TT

149

129

1.39(0.98–1.98)

0.065

120

118

1.01(0.69–1.47)

0.975

Recessive

CC + CT

227

239

1

213

209

1

TT

29

20

1.63(0.88–2.99)

0.118

18

19

0.88(0.44–1.75)

0.710

Log-additive

—

—

—

1.34(1.02–1.76)

0.034

—

—

0.98(0.73–1.32)

0.891

rs13146272

Co-dominant

CC

93

98

1

84

90

1

CA

127

127

1.04(0.71–1.52)

0.846

112

98

1.20(0.79–1.82)

0.384

AA

36

34

1.05(0.60–1.83)

0.857

34

40

0.76(0.43–1.34)

0.348

Dominant

CC

93

98

1

84

90

1

CA + AA

163

161

1.04(0.72–1.50)

0.826

146

138

1.07(0.72–1.58)

0.741

Recessive

CC + CA

220

225

1

196

188

1

AA

36

34

1.03(0.62–1.72)

0.910

34

40

0.69(0.41–1.16)

0.161

Log-additive

—

—

—

1.03(0.79–1.34)

0.829

—

—

0.93(0.71–1.22)

0.641

rs3736455

Co-dominant

TT

91

88

1

77

86

1

TG

131

138

0.98(0.55–1.73)

0.941

123

102

1.26(0.83–1.92)

0.270

GG

34

32

0.91(0.62–1.34)

0.628

31

39

0.76(0.42–1.35)

0.344

Dominant

TT

91

88

1

77

86

1

TG + GG

165

170

0.92(0.64–1.33)

0.669

154

141

1.12(0.75–1.66)

0.577

Recessive

TT + TG

222

226

1

200

188

1

GG

34

32

1.04(0.61–1.75)

0.893

31

39

0.66(0.39–1.12)

0.123

Log-additive

—

—

—

0.97(0.74–1.27)

0.809

—

—

0.94(0.71–1.24)

0.671

rs1053094

Co-dominant

TT

98

114

1

94

95

1

TA

127

121

1.21(0.83–1.75)

0.328

106

104

1.00(0.66–1.49)

0.981

AA

31

23

1.61(0.87–2.97)

0.130

31

29

1.14(0.63–2.06)

0.675

Dominant

TT

98

114

1

94

95

1

TA + AA

158

144

1.27(0.89–1.81)

0.194

137

133

1.03(0.70–1.50)

0.899

Recessive

TT + TA

225

235

1

200

199

1

AA

31

23

1.45(0.81–2.59)

0.207

31

29

1.14(0.65–1.99)

0.647

Log-additive

—

—

—

1.25(0.95–1.63)

0.115

—

—

1.05(0.79–1.38)

0.750

rs56413992

Co-dominant

CC

145

171

1

143

155

1

CT

100

83

1.44(0.99–2.08)

0.056

75

61

1.38(0.91–2.10)

0.133

TT

11

5

2.88(0.96–8.69)

0.060

13

10

1.39(0.58–3.34)

0.465

Dominant

CC

145

171

1

143

155

1

CT + TT

111

88

1.51(1.05–2.17)

0.025

88

71

1.38(0.93–2.05)

0.112

Recessive

CC + CT

245

254

1

218

216

1

TT

11

5

2.52(0.84–7.52)

0.098

13

10

1.26(0.53–3.00)

0.607

Log-additive

—

—

—

1.51(1.09–2.08)

0.012

—

—

1.28(0.92–1.78)

0.137