Table 7 Association of CYP4V2 gene SNP polymorphisms with CHD risk stratified analysis by drinking

rs1398007

Co-dominant

CC

67

106

1

151

134

1

CT

93

81

1.80(1.17–2.78)

0.008

129

127

0.83(0.59–1.18)

0.301

TT

20

13

2.41(1.11–5.25)

0.026

27

26

0.89(0.49–1.61)

0.698

Dominant

CC

67

106

1

151

134

1

CT + TT

113

94

1.88(1.24–2.86)

0.003

156

153

0.84(0.61–1.17)

0.309

Recessive

CC + CT

160

187

1

280

261

1

TT

20

13

1.79(0.85–3.77)

0.124

27

26

0.97(0.55–1.72)

0.914

Log-additive

—

—

—

1.65(1.19–2.30)

0.003

—

—

0.90(0.70–1.16)

0.404

rs13146272

Co-dominant

CC

76

73

1

101

115

1

CA

86

98

0.83(0.53–1.29)

0.400

153

127

1.46(1.01–2.09)

0.042

AA

18

29

0.58(0.29–1.14)

0.116

52

45

1.26(0.77–2.05)

0.354

Dominant

CC

76

73

1

101

115

1

CA + AA

104

127

0.77(0.51–1.17)

0.224

205

172

1.40(1.00–1.97)

0.052

Recessive

CC + CA

162

171

1

254

242

1

AA

18

29

0.64(0.34–1.21)

0.174

52

45

1.02(0.66–1.59)

0.920

Log-additive

—

—

—

0.78(0.57–1.07)

0.118

—

—

1.18(0.93–1.49)

0.163

rs3736455

Co-dominant

TT

74

69

1

94

105

1

TG

89

101

0.81(0.52–1.25)

0.337

165

139

1.41(0.98–2.02)

0.066

GG

17

29

0.54(0.27–1.07)

0.078

48

42

1.23(0.74–2.04)

0.425

Dominant

TT

74

69

1

94

105

1

TG + GG

106

130

0.75(0.49–1.14)

0.174

213

181

1.36(0.96–1.93)

0.080

Recessive

TT + TG

163

170

1

259

244

1

GG

17

29

0.61(0.32–1.16)

0.130

48

42

1.00(0.64–1.58)

0.990

Log-additive

—

—

—

0.75(0.55–1.03)

0.079

—

—

1.17(0.91–1.49)

0.216

rs1053094

Co-dominant

TT

65

88

1

127

121

1

TA

92

95

1.24(0.80–1.93)

0.332

141

130

1.01(0.71–1.42)

0.977

AA

23

17

2.04(0.99–4.20)

0.055

39

35

1.11(0.66–1.88)

0.701

Dominant

TT

65

88

1

127

121

1

TA + AA

115

112

1.36(0.89–2.06)

0.156

180

165

1.03(0.74–1.43)

0.877

Recessive

TT + TA

157

183

1

268

251

1

AA

23

17

1.81(0.91–3.60)

0.090

39

35

1.11(0.67–1.81)

0.690

Log-additive

—

—

—

1.36(0.99–1.87)

0.061

—

—

1.04(0.82–1.32)

0.758

rs56413992

Co-dominant

CC

94

143

1

194

183

1

CT

80

53

2.26(1.45–3.51)

 < 0.001

95

91

1.04(0.73–1.48)

0.846

TT

6

4

2.66(0.70–10.10)

0.150

18

11

1.59(0.73–3.49)

0.245

Dominant

CC

94

143

1

194

183

1

CT + TT

86

57

2.29(1.48–3.52)

 < 0.001

113

102

1.10(0.78–1.54)

0.593

Recessive

CC + CT

174

196

1

289

274

1

TT

6

4

2.00(0.53–7.52)

0.305

18

11

1.57(0.72–3.42)

0.252

Log-additive

—

—

—

2.07(1.40–3.06)

 < 0.001

—

—

1.13(0.86–1.50)

0.386