Fig. 4
From: Identification of genetic variants in two families with Keratoconus
The reports of sequencing and cross-species conservation analysis are shown. a The Sanger sequencing in the variant and wild-type samples is shown. The variant c.622A > G in TSC1 is indicated (arrow). b The single nucleotide polymorphism (SNP) rs761232139 in ALDH3A1 is indicated (arrow). c The multiple alignments demonstrate that the arginine at codon 208 in TSC1 is highly conserved. A black bar highlights the codon 208 in TSC1