Fig. 9

Effects of SERPINA3 overexpression on the colon cancer cell migration, proliferation and EMT. (A) HT29 cells were transfected with pcDNA overexpressing SERPINA3 or pcDNA, SERPINA3 expression was determined by evaluated by qRT-PCR. (B) HT29 cell caspase-3 activity was determined in different groups (pcDNA, pcDNA-SERPINA3). (C) HT29 cell caspase-9 activity was determined in different groups (pcDNA, pcDNA-SERPINA3). (D) HT29 cell migratory capacity was determined in different groups (pcDNA, pcDNA-SERPINA3). (E) HT29 cell proliferation was determined in different groups (pcDNA, pcDNA-SERPINA3). (F) HT29 cell EMT-related marker expression was evaluated in different groups (pcDNA, pcDNA-SERPINA3). N = 3. “*P < 0.05 and **P < 0.01”