Screening of premature ovarian insufficiency associated genes in Hungarian patients with next generation sequencing

Table 3 Clinical characteristics and molecular findings of POI patients carrying potential causative variants

Patients ID	Menarche age (year)	POI onset age (year)	Hormone values		Gene
Patients ID	Menarche age (year)	POI onset age (year)	FSH (lU/L)	LH (ng/mL)	Gene
P03	13	34	89,53	0,010	USP9X, DACH2
P04	12	34	98,19	0,016	XPNPEP2
P05	14	16	44,23	0,674	LHCGR
P08	13	15	139,25	0,041	AIRE
P09	11	39	51,48	0,092	DAZL
P10	16	24	63,57	1,212	FMR1
P11	11	25	106,59	0,144	EIF2B4
P12	17	33	45,10	0,169	EIF2B4
P14	12	39	72,46	0,010	DACH2
P18	12	37	76,40	0,016	POLG
P19	14	39	70,86	0,169	XPNPEP2
P20	14	39	48,30	0,092	GDF9, POLG
P22	13	34	51,12	1,285	EIF2B2
P23	11	39	140,93	0,169	GALT
P24	12	36	133,90	0,041	ATM, NOBOX
P26	12	39	44,04	0,092	ATM, GALT, NOBOX
P29	15	36	43,10	0,169	GALT
P31	11	28	55,20	0,373	EIF2B4, GALT
P32	11	37	65,10	0,041	GALT
P36	13	29	59,68	0,100	DAZL
P37	11	33	60,27	0,900	HS6ST2
P38	17	24	44,28	0,050	HS6ST2
P39	14	30	47,53	0,850	HS6ST2
P40	13	31	59,19	0,145	EIF2B4, NOBOX
P42	14	38	80,70	0,592	AIRE
P44	10	27	61,86	1,230	GALT
P45	12	30	80,00	0,900	GALT
P48	14	32	63,20	0,530	GALT

ISSN: 1755-8794