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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Comprehensive characterization of immunogenic cell death in acute myeloid leukemia revealing the association with prognosis and tumor immune microenvironment

Fig. 3

Identification of differentially expressed genes (DEGs) and potential signaling pathways in the subtypes. (A) Volcano plot showing the quantified DEG distribution between the ICD-high and the ICD-low subtype with threshold of |log2 Fold change| > 2 and P < 0.05 in TCGA cohort; (B) Heatmap shows the expression of DEG in different subtypes; (C, D, E) Biological Process, Cellular Component and Molecular Function in GO signaling pathway enrichment analysis. The size of dots represents gene counts and the color of dots represents– log10 (p. adjust-value); (F) GSEA analysis identifies potential signaling pathways between subtypes; (G) KEGG pathway analysis; (H) Comparison of somatic mutations between subtypes

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BMC Medical Genomics

ISSN: 1755-8794

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